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Master Cleanse also called the lemonade diet or lemon detox diet is a modified juice fast that permits no food, substituting tea and lemonade made with maple syrup and cayenne pepper. The diet was developed by Stanley Burroughs, who initially marketed it in the s, and revived it his book The Master Cleanser. There is no evidence that the diet removes any toxins or that it achieves anything beyond temporary weight loss, followed by rapidly regaining the lost weight. Though unlikely to be harmful over the short term, Master Cleanse and similar programs can be harmful over the long term. The diet lacks protein, fatty acids, and other essential nutrients and depends entirely on carbohydrates for calories. The daily laxative regimen can cause electrolyte imbalances and disrupt the normal gastrointestinal microbiome. In the longer run, staying on the Master Cleanse diet could result in severe metabolic acidosis, which can lead to coma or death. Nutritionist Jane Clark points to a lack of essential nutrients in this program, citing a deficiency of protein, vitamins, and minerals.